Improvement of Human Epidermal Barrier Structure and Lipid Profile in Xerotic- and Atopic-Prone Skin via Application of a Plant-Oil and Urea Containing pH 4.5 Emulsion

Epidermal barrier dysfunction can lead to xerotic skin and promote disorders like atopic dermatitis. Atopic is characterized by reduced water-retaining compounds, altered lipid composition elevated pH. Against this background, a study was conducted investigate the impact of specific care product on epidermal function in dry atopic-prone skin. A marketed pH 4.5 cosmetic formulation containing 10% urea plant oils evaluated 25 subjects with Measurements hydration, pH, were performed before after 3 weeks usage. Additionally, visual scoring stratum corneum analysis using electron microscopy composition. An improved hydration compared untreated area tendency decrease baseline surface observed. The showed dryness, roughness, tension through application. Furthermore, matrix terms content organization. combination an acidic product’s relevant effective shown be beneficial improving function, structure appearance recommended for